CalaVida™ · Liposomal
Pura Methylate Liposomal Methyl B-Complex
Complete B-complex, methylated.
A complete liposomal methyl B-complex. Pura Methylate delivers all eight B vitamins plus TMG and milk thistle, in a phosphatidylcholine liposomal liquid — daily support for energy metabolism, balanced methylation, and cellular function. 50 mL pump bottle, 50 servings.*
- Flavor
- Lemon Raspberry
- Serving size
- 1 mL (2 pumps) · 50 mL bottle
$45.00
Key Benefits
- ✓ Supports daily energy metabolism and cellular function*
- ✓ Supports balanced methylation and normal homocysteine metabolism*
- ✓ Supports healthy neurotransmission, focus, and mood balance*
- ✓ Includes TMG (methyl donor) and milk thistle for liver/detox positioning*
- ✓ All eight B vitamins in a convenient liposomal pump*
Important
Contains ethanol. Provides 500 mcg biotin per serving, which can interfere with some lab tests — tell your healthcare provider before testing. Consult a professional before use if pregnant, nursing, taking medication, or sensitive to B vitamins.
The science behind it
Complete B-vitamin blend — energy metabolism
B vitamins are essential cofactors and coenzymes in core metabolic pathways; the supported lane is normal energy metabolism, cellular function, and daily nutritional repletion. [1,2,3,4,5,6,7,8,9]*
Methylation & homocysteine (Folate, B12, B6)
Folate (calcium folinate), methyl B12, and B6 are central to one-carbon and homocysteine metabolism; this blend supports balanced methylation rather than relying solely on methylfolate. [4,5,6,9]*
TMG & milk thistle
TMG (betaine) contributes methyl-donor support, while milk thistle seed extract supports liver and natural-detoxification positioning. [10,11]*
Liposomal phospholipid delivery
A phosphatidylcholine liposomal matrix supports the liquid delivery format. [12,13]*
Supplement Facts
| Active Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Thiamin (B1, as Thiamine HCl) | 12 mg | 1000% |
| Riboflavin (as Riboflavin-5-Phosphate) | 3.6 mg | 277% |
| Niacin (as Niacin, Niacinamide) | 10 mg | 63% |
| Vitamin B6 (as Pyridoxine HCl) | 6.7 mg | 394% |
| Folate (as Calcium Folinate) | 850 mcg DFE | 213% |
| Vitamin B12 (as Methylcobalamin) | 500 mcg | 20,833% |
| Biotin | 500 mcg | 1,667% |
| Pantothenic Acid (as Calcium d-Pantothenate) | 22.5 mg | 450% |
| Proprietary Blend — phosphatidylcholine, milk thistle seed extract, TMG (betaine) | 125 mg | — |
Amounts are preliminary and shown from the formulation sheet; final values and units are pending label verification.
How to use
Take 2 pumps by mouth. Hold in the mouth 30–90 seconds before swallowing, then repeat to your desired dose or as directed by a healthcare professional. Best on an empty stomach, at least 10 minutes before meals.
References
- NIH Office of Dietary Supplements. Thiamin — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Riboflavin — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Niacin — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Vitamin B6 — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Folate — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Vitamin B12 — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Biotin — Health Professional Fact Sheet.
- NIH Office of Dietary Supplements. Pantothenic Acid — Health Professional Fact Sheet.
- Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy — A Review. Nutrients (2016). NIH/PMC.
- Arumugam MK, et al. Beneficial Effects of Betaine: A Comprehensive Review. Biology (2021). NIH/PMC.
- NIH NCCIH. Milk Thistle: Usefulness and Safety.
- Nsairat H, et al. Liposomes: structure, composition, types, and clinical applications. Heliyon (2022). NIH/PMC.
- Rudzinska M, et al. Liposomes as Carriers of Bioactive Compounds in Human Nutrition. Foods (2024). NIH/PMC.
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.